About Us

At Fagus Therapeutics, our mission is to confront the health challenges that come with ageing. With age, the likelihood of developing conditions like arthritis, osteoporosis, and diabetes climbs, diminishing our quality of life and exerting pressure on global healthcare systems.

To tackle this, we’ve adopted an innovative strategy that targets senescent cells – the culprits behind many age-related diseases. Our method uses targeted antibodies designed to recognise and attach to these cells, delivering a therapeutic agent that prompts them to undergo natural cell death. This approach holds the promise of lightening the load of age-related diseases on both individuals and healthcare services.

Our efforts are bolstered by a team of seasoned experts in ageing and cellular biology. These advisors – accomplished scientists and clinicians with a profound understanding of the ageing process – steer our strategic direction and research initiatives. Their invaluable expertise ensures our strategies are anchored in cutting-edge scientific research, poised to drive significant advancements in treating age-related conditions.

Dedicated to deepening our grasp on how to effectively target senescent cells, Fagus Therapeutics is committed to mitigating the effects of ageing on individuals and healthcare systems alike. Guided by our distinguished advisors, we’re pushing the boundaries of research into age-related diseases, working towards a future where ageing doesn’t necessarily equate to illness.

Board of Directors

Dr Gulam Altab

CEO/CSO

Umar Gulam

CFO

Fatima Aitbenhaddou

Non-Executive Director

Gulam Ahmed

Non-Executive Director

Board of Advisors

Prof. João Pedro de Magalhães

Scientific Advisor

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Dr Gulam Altab

CEO/CSO

Dr. Gulam Altab (BSc, MSc, MRes, and PhD) is a dedicated researcher specialising in the ageing of skeletal muscle and its response to caloric restriction. His PhD thesis focused on understanding the intricate changes in non-coding RNAs that occur during muscle ageing in rats. During this research, he aimed to identify key regulatory elements and biomarkers, with a specific focus on whether these changes could be influenced by dietary interventions, especially caloric restriction.

Gulam’s academic journey includes an MSc in Stem Cells and Regenerative Medicine and an MRes in Musculoskeletal Ageing. He has extensive experience in various research techniques and methodologies, including RNA sequencing, single-cell analysis, and molecular biology. He possesses a deep understanding of the complex cellular pathways and molecular mechanisms that underlie the ageing of tissues.

Currently, Gulam is deeply interested in the potential of targeted anti-ageing therapeutics. He firmly believes that slowing the ageing process is not only about extending our years but also enhancing the quality of our lives. It represents a journey towards a healthier, more fulfilling future.

“Slowing the ageing process is not just about increasing our lifespan; it’s an opportunity to improve our quality of life. It’s a path towards a healthier, more rewarding future.”

Umar

Umar Gulam

CFO

Umar is a founder member and the Chief Financial Officer of Fagus Therapeutics. He has a plethora of expertise working in the financial services industry, equipped with a solid foundation in accounting. Umar will be responsible for managing the company’s finances and strategically accelerating growth thanks to his broad range of financial talents, entrepreneurial enthusiasm, and organisational abilities.

Email: umar@fagustherapeutics.com

FA

Fatima Aitbenhaddou

Non-Executive Director

Fatima Aitbenhaddou is a scientist with more than 22 years of expertise in life sciences management. She has worked for renowned global companies, gaining industry experience in Immunology technical methods, including Hybridoma cell line development, antibody manufacturing processes, Immunoassay development, Bioconjugation of protein and antibody, as well as Analytical and biochemical techniques. Email: fatima@fagustherapeutics.com
Ahmed

Gulam Ahmed

Non-Executive Director

Gulam Ahmed LLB (Hons) LLM Since being called to the bar in 1997, Gulam Ahmed has been practising as a specialist criminal barrister. This has included homicide, terrorism and fraud. Over the years, Gulam Ahmed has defended in some of the highest profile cases attracting media attention. His dedication, strong advocacy skills and analytical ability have made him successful and placed him very much in demand. Gulam Ahmed is a founder member of Fagus and its Chairman. Although he remains in independent practice, Gulam Ahmed guides Fagus’s board on business strategy, governance, delivery of services and products, and finance. Gulam Ahmed plays an integral role with the board in growing Fagus whilst maintaining quality and excellence.

Email: ahmed@fagustherapeutics.com

JP

João Pedro de Magalhães

Scientific Advisor

Prof de Magalhaes graduated in Microbiology in 1999 from the Escola Superior de Biotecnologia in his hometown of Porto, Portugal, and then obtained his PhD in 2004 from the University of Namur in Belgium. Following a postdoc with genomics pioneer Prof George Church at Harvard Medical School in Boston, USA, in 2008 Prof de Magalhaes was recruited to the University of Liverpool in the UK to establish his own group on genomic approaches to ageing. In 2022, Prof de Magalhaes was recruited to the University of Birmingham as Chair of Molecular Biogerontology where he currently leads the Genomics of Ageing and Rejuvenation Lab [http://rejuvenomicslab.com/].
His lab studies the ageing process and how we can manipulate it to fend off age-related diseases and improve human health. The lab’s research integrates different strategies, but its focal point is developing and applying experimental and computational methods that help bridge the gap between genotype and phenotype, a major challenge of the post-genome era, and help decipher the human genome and how it regulates complex processes like ageing.
Notably, his lab is a world-leader in employing genomics and bioinformatics to study ageing with pioneering work in studying gene networks of ageing and in sequencing and analysing genomes from long-lived species. Prof de Magalhaes has authored over 100 publications and given over 100 invited talks, including three TEDx talks. His research has also been widely featured in the popular press (BBCCNN, the Washington Post, the Financial Times and many others).